The Correlation between Physical Crosslinking and Water-Soluble Drug Release from Chitosan-Based Microparticles

Microparticles containing water-soluble zidovudine were prepared by spray-drying using chitosan glutamate and beta-glycerophosphate as an ion crosslinker (CF). The Box-Behnken design was applied to optimize the microparticles in terms of their drug loading and release behavior. Physicochemical studi...

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Principais autores: Emilia Szymańska (Autor), Katarzyna Woś-Latosi (Autor), Julia Jacyna (Autor), Magdalena Dąbrowska (Autor), Joanna Potaś (Autor), Michał Jan Markuszewski (Autor), Katarzyna Winnicka (Autor)
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Publicado em: MDPI AG, 2020-05-01T00:00:00Z.
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