The Correlation between Physical Crosslinking and Water-Soluble Drug Release from Chitosan-Based Microparticles

The Correlation between Physical Crosslinking and Water-Soluble Drug Release from Chitosan-Based Microparticles

Microparticles containing water-soluble zidovudine were prepared by spray-drying using chitosan glutamate and beta-glycerophosphate as an ion crosslinker (CF). The Box-Behnken design was applied to optimize the microparticles in terms of their drug loading and release behavior. Physicochemical studi...

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Main Authors: Emilia Szymańska (Author), Katarzyna Woś-Latosi (Author), Julia Jacyna (Author), Magdalena Dąbrowska (Author), Joanna Potaś (Author), Michał Jan Markuszewski (Author), Katarzyna Winnicka (Author)
Format: Book
Published: MDPI AG, 2020-05-01T00:00:00Z.
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