The Correlation between Physical Crosslinking and Water-Soluble Drug Release from Chitosan-Based Microparticles

• Asıl Yazarlar: Emilia Szymańska (Yazar), Katarzyna Woś-Latosi (Yazar), Julia Jacyna (Yazar), Magdalena Dąbrowska (Yazar), Joanna Potaś (Yazar), Michał Jan Markuszewski (Yazar), Katarzyna Winnicka (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2020-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Microparticles containing water-soluble zidovudine were prepared by spray-drying using chitosan glutamate and beta-glycerophosphate as an ion crosslinker (CF). The Box-Behnken design was applied to optimize the microparticles in terms of their drug loading and release behavior. Physicochemical studi...