Down-Regulation of the Na+-Coupled Phosphate Transporter NaPi-IIa by AMP-Activated Protein Kinase

• Päätekijät: Miribane Dërmaku-Sopjani (Tekijä), Ahmad Almilaji (Tekijä), Tatsiana Pakladok (Tekijä), Carlos Munoz (Tekijä), Zohreh Hosseinzadeh (Tekijä), María Blecua (Tekijä), Mentor Sopjani (Tekijä), Florian Lang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Karger Publishers, 2013-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Background/Aims: The Na+-coupled phosphate transporter NaPi-IIa is the main carrier accomplishing renal tubular phosphate reabsorption. It is driven by the electrochemical Na+ gradient across the apical cell membrane, which is maintained by Na+ extrusion across the basolateral cell membrane through...