Evaluation of Novel 3-Hydroxyflavone Analogues as HDAC Inhibitors against Colorectal Cancer

• Váldodahkkit: Subhankar Biswas (Dahkki), Neetinkumar D. Reddy (Dahkki), B. S. Jayashree (Dahkki), C. Mallikarjuna Rao (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2018-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Alteration of epigenetic enzymes is associated with the pathophysiology of colon cancer with an overexpression of histone deacetylase 8 (HDAC8) enzyme in this tissue. Numerous reports suggest that targeting HDAC8 is a viable strategy for developing new anticancer drugs. Flavonols provide a rich sour...