Evaluation of Novel 3-Hydroxyflavone Analogues as HDAC Inhibitors against Colorectal Cancer

• 主要な著者: Subhankar Biswas (著者), Neetinkumar D. Reddy (著者), B. S. Jayashree (著者), C. Mallikarjuna Rao (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2018-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Alteration of epigenetic enzymes is associated with the pathophysiology of colon cancer with an overexpression of histone deacetylase 8 (HDAC8) enzyme in this tissue. Numerous reports suggest that targeting HDAC8 is a viable strategy for developing new anticancer drugs. Flavonols provide a rich sour...