Profiling patent compounds in lipid nanoparticle formulations of siRNA

• Главные авторы: Yunfeng Han (Автор), Mengyang Wang (Автор), Yu Chen (Автор), Defang Ouyang (Автор), Ying Zheng (Автор), Yuanjia Hu (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2024-12-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Lipid nanoparticles (LNPs) have emerged as a prominent delivery system for nucleic acid drugs, attracting significant attention, especially through the successful development of several commercial products. As a key component in LNPs, cationic lipids have long served as a key technical barrier to bl...