Improved endurance capacity of diabetic mice during SGLT2 inhibition: Role of AICARP, an AMPK activator in the soleus

• Главные авторы: Shintaro Nakamura (Автор), Yasutaka Miyachi (Автор), Akihito Shinjo (Автор), Hisashi Yokomizo (Автор), Masatomo Takahashi (Автор), Kohta Nakatani (Автор), Yoshihiro Izumi (Автор), Hiroko Otsuka (Автор), Naoichi Sato (Автор), Ryuichi Sakamoto (Автор), Takashi Miyazawa (Автор), Takeshi Bamba (Автор), Yoshihiro Ogawa (Автор)
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• Опубликовано: Wiley, 2023-12-01T00:00:00Z.
• Предметы: article
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Abstract Background Diabetes is associated with an increased risk of deleterious changes in muscle mass and function or sarcopenia, leading to physical inactivity and worsening glycaemic control. Given the negative energy balance during sodium-glucose cotransporter‐2 (SGLT2) inhibition, whether SGLT...