Improved endurance capacity of diabetic mice during SGLT2 inhibition: Role of AICARP, an AMPK activator in the soleus

• Main Authors: Shintaro Nakamura (Author), Yasutaka Miyachi (Author), Akihito Shinjo (Author), Hisashi Yokomizo (Author), Masatomo Takahashi (Author), Kohta Nakatani (Author), Yoshihiro Izumi (Author), Hiroko Otsuka (Author), Naoichi Sato (Author), Ryuichi Sakamoto (Author), Takashi Miyazawa (Author), Takeshi Bamba (Author), Yoshihiro Ogawa (Author)
• Format: Book
• Published: Wiley, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Diabetes is associated with an increased risk of deleterious changes in muscle mass and function or sarcopenia, leading to physical inactivity and worsening glycaemic control. Given the negative energy balance during sodium-glucose cotransporter‐2 (SGLT2) inhibition, whether SGLT...