Physiologically based radiopharmacokinetic (PBRPK) modeling to simulate and analyze radiopharmaceutical therapies: studies of non-linearities, multi-bolus injections, and albumin binding

Abstract Background We aimed to develop a publicly shared computational physiologically based pharmacokinetic (PBPK) model to reliably simulate and analyze radiopharmaceutical therapies (RPTs), including probing of hot-cold ligand competitions as well as alternative injection scenarios and drug desi...

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Main Authors: Ali Fele-Paranj (Author), Babak Saboury (Author), Carlos Uribe (Author), Arman Rahmim (Author)
Format: Book
Published: SpringerOpen, 2024-01-01T00:00:00Z.
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3rd Floor Main Library

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