Induction Apoptosis of Erinacine A in Human Colorectal Cancer Cells Involving the Expression of TNFR, Fas, and Fas Ligand via the JNK/p300/p50 Signaling Pathway With Histone Acetylation

• मुख्य लेखकों: Ko-Chao Lee (लेखक), Kam-Fai Lee (लेखक), Shui-Yi Tung (लेखक), Wen-Shih Huang (लेखक), Li-Ya Lee (लेखक), Wan-Ping Chen (लेखक), Chin-Chu Chen (लेखक), Chih-Chuan Teng (लेखक), Chien-Heng Shen (लेखक), Meng-Chiao Hsieh (लेखक), Hsing-Chun Kuo (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Erinacine A, which is one of the major bioactive diterpenoid compounds extracted from cultured mycelia of H. erinaceus, displays great antitumorigenic activity. However, the molecular mechanisms underlying erinacine A inducing cancer cell apoptosis in colorectal cancer (CRC) remain unclear. This stu...