Naldemedine-induced perforation of a diverticulum in the sigmoid colon of a patient with opioid-related constipation: a case report

• Hoofdauteurs: Hayato Yokota (Auteur), Yumiko Akamine (Auteur), Mizuki Kobayashi (Auteur), Takuro Kitabayashi (Auteur), Misato Horie (Auteur), Tentaro Endo (Auteur), Takechiyo Yamada (Auteur), Masafumi Kikuchi (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2024-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background Naldemedine is an orally available peripherally acting μ-opioid receptor antagonist approved to treat opioid-induced constipation (OIC). It is contraindicated for patients with known or suspected gastrointestinal obstruction to protect against naldemedine-induced perforation. Her...