Efficient Knockdown and Lack of Passenger Strand Activity by Dicer-Independent shRNAs Expressed from Pol II-Driven MicroRNA Scaffolds

The expression of short hairpin RNAs (shRNAs) may result in unwanted activity from the co-processed passenger strand. Recent studies have shown that shortening the stem of conventional shRNAs abolishes passenger strand release. These Dicer-independent shRNAs, expressed from RNA polymerase III (Pol I...

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主要な著者: Erik Kaadt (著者), Sidsel Alsing (著者), Claudia R. Cecchi (著者), Christian Kroun Damgaard (著者), Thomas J. Corydon (著者), Lars Aagaard (著者)
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出版事項: Elsevier, 2019-03-01T00:00:00Z.
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3rd Floor Main Library

予約・返却請求 3rd Floor Main Library
請求記号: A1234.567
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