The potential roles of Nrf2/Keap1 signaling in anticancer drug interactions

• Ngā kaituhi matua: Jingya Wang (Author), Jin Yang (Author), Mingnan Cao (Author), Zhigang Zhao (Author), Baoshan Cao (Author), Siwang Yu (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2021-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Nuclear factor (erythroid-derived 2)-related factor 2 (Nrf2), together with its suppressive binding partner Kelch-like ECH-associated protein 1 (Keap1), regulates cellular antioxidant response and drug metabolism. The roles of Nrf2/Keap1 signaling in the pathology of many diseases have been extensiv...