The potential roles of Nrf2/Keap1 signaling in anticancer drug interactions

• Główni autorzy: Jingya Wang (Autor), Jin Yang (Autor), Mingnan Cao (Autor), Zhigang Zhao (Autor), Baoshan Cao (Autor), Siwang Yu (Autor)
• Format: Książka
• Wydane: Elsevier, 2021-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Nuclear factor (erythroid-derived 2)-related factor 2 (Nrf2), together with its suppressive binding partner Kelch-like ECH-associated protein 1 (Keap1), regulates cellular antioxidant response and drug metabolism. The roles of Nrf2/Keap1 signaling in the pathology of many diseases have been extensiv...