Inhibitory Effect of Chlorogenic Acid Analogues Comprising Pyridine and Pyrimidine on α-MSH-Stimulated Melanogenesis and Stability of Acyl Analogues in Methanol

• Prif Awduron: Jaeuk Sim (Awdur), Srinu Lanka (Awdur), Jeong-Woong Jo (Awdur), Chhabi Lal Chaudhary (Awdur), Manjunatha Vishwanath (Awdur), Chan-Hyun Jung (Awdur), Young-Hee Lee (Awdur), Eun-Yeong Kim (Awdur), Young-Soo Kim (Awdur), Soon-Sil Hyun (Awdur), Hee-Soon Lee (Awdur), Kiho Lee (Awdur), Seung-Yong Seo (Awdur), Mayavan Viji (Awdur), Jae-Kyung Jung (Awdur)
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• Cyhoeddwyd: MDPI AG, 2021-11-01T00:00:00Z.
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In continuation of studies for α-MSH stimulated melanogenesis inhibitors, we have evaluated the design, synthesis, and activity of a new series of chlorogenic acid (CGA) analogues comprising pyridine, pyrimidine, and diacyl derivatives. Among nineteen synthesized compounds, most of them (fifteen) ex...