Inhibitory Effect of Chlorogenic Acid Analogues Comprising Pyridine and Pyrimidine on α-MSH-Stimulated Melanogenesis and Stability of Acyl Analogues in Methanol

• Main Authors: Jaeuk Sim (Author), Srinu Lanka (Author), Jeong-Woong Jo (Author), Chhabi Lal Chaudhary (Author), Manjunatha Vishwanath (Author), Chan-Hyun Jung (Author), Young-Hee Lee (Author), Eun-Yeong Kim (Author), Young-Soo Kim (Author), Soon-Sil Hyun (Author), Hee-Soon Lee (Author), Kiho Lee (Author), Seung-Yong Seo (Author), Mayavan Viji (Author), Jae-Kyung Jung (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In continuation of studies for α-MSH stimulated melanogenesis inhibitors, we have evaluated the design, synthesis, and activity of a new series of chlorogenic acid (CGA) analogues comprising pyridine, pyrimidine, and diacyl derivatives. Among nineteen synthesized compounds, most of them (fifteen) ex...