Delivering therapeutic RNA into the brain using extracellular vesicles

• Үндсэн зохиолчид: Paniz Shirmast (Зохиогч), Mahdi Abedinzadeh Shahri (Зохиогч), Austin Brent (Зохиогч), Adi Idris (Зохиогч), Nigel A.J. McMillan (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2024-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

RNA science has experienced a surge, particularly its application to vaccine and therapeutic development. Delivery of RNA molecules into the brain remains one of the biggest therapeutic challenges with the blood-brain barrier excluding most drug-delivery modalities such as lipid nanoparticles. As RN...