Delivering therapeutic RNA into the brain using extracellular vesicles

• Main Authors: Paniz Shirmast (Author), Mahdi Abedinzadeh Shahri (Author), Austin Brent (Author), Adi Idris (Author), Nigel A.J. McMillan (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

RNA science has experienced a surge, particularly its application to vaccine and therapeutic development. Delivery of RNA molecules into the brain remains one of the biggest therapeutic challenges with the blood-brain barrier excluding most drug-delivery modalities such as lipid nanoparticles. As RN...