Differently increased volumes of multiple brain areas in Npc1 mutant mice following various drug treatments

• প্রধান লেখক: Veronica Antipova (লেখক), Diana Heimes (লেখক), Katharina Seidel (লেখক), Jennifer Schulz (লেখক), Oliver Schmitt (লেখক), Carsten Holzmann (লেখক), Arndt Rolfs (লেখক), Hans-Jürgen Bidmon (লেখক), Estibaliz González de San Román Martín (লেখক), Pitter F. Huesgen (লেখক), Katrin Amunts (লেখক), Jonas Keiler (লেখক), Niels Hammer (লেখক), Martin Witt (লেখক), Andreas Wree (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

BackgroundNiemann-Pick disease type C1 (NPC1, MIM 257220) is a heritable lysosomal storage disease characterized by a progressive neurological degeneration that causes disability and premature death. A murine model of Npc1−/− displays a rapidly progressing form of Npc1 disease, which is characterize...