The Impact of Melatonin Supplementation and NLRP3 Inflammasome Deletion on Age-Accompanied Cardiac Damage

• Автори: Ramy K. A. Sayed (Автор), Marisol Fernández-Ortiz (Автор), Ibtissem Rahim (Автор), José Fernández-Martínez (Автор), Paula Aranda-Martínez (Автор), Iryna Rusanova (Автор), Laura Martínez-Ruiz (Автор), Reem M. Alsaadawy (Автор), Germaine Escames (Автор), Darío Acuña-Castroviejo (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2021-08-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

To investigate the role of NLRP3 inflammasome in cardiac aging, we evaluate here morphological and ultrastructural age-related changes of cardiac muscles fibers in wild-type and NLRP3-knockout mice, as well as studying the beneficial effect of melatonin therapy. The results clarified the beginning o...