The Effect of Length and Structure of Attached Polyethylene Glycol Chain on Hydrodynamic Radius, and Separation of PEGylated Human Serum Albumin by Chromatography

• Asıl Yazarlar: Parvin Akbarzadehlaleh (Yazar), Mona Mirzaei (Yazar), Mahdiyeh Mashahdi-keshtiban (Yazar), Hamid Reza Heidari (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Tabriz University of Medical Sciences, 2021-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Purpose: This study focuses on the effect of length and structure of attached polyethylene glycol (PEG) chain on hydrodynamic radius (Rh ) and chromatographic retention of PEGylated protein. To this aim human serum albumin (HSA) as a standard protein was PEGylated site specifically with mPEG-maleimi...