The Effect of Length and Structure of Attached Polyethylene Glycol Chain on Hydrodynamic Radius, and Separation of PEGylated Human Serum Albumin by Chromatography

Purpose: This study focuses on the effect of length and structure of attached polyethylene glycol (PEG) chain on hydrodynamic radius (Rh ) and chromatographic retention of PEGylated protein. To this aim human serum albumin (HSA) as a standard protein was PEGylated site specifically with mPEG-maleimi...

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Auteurs principaux: Parvin Akbarzadehlaleh (Auteur), Mona Mirzaei (Auteur), Mahdiyeh Mashahdi-keshtiban (Auteur), Hamid Reza Heidari (Auteur)
Format: Livre
Publié: Tabriz University of Medical Sciences, 2021-09-01T00:00:00Z.
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