Orally Bioavailable Proteolysis-Targeting Chimeras: An Innovative Approach in the Golden Era of Discovering Small-Molecule Cancer Drugs

Orally Bioavailable Proteolysis-Targeting Chimeras: An Innovative Approach in the Golden Era of Discovering Small-Molecule Cancer Drugs

Proteolysis-targeting chimeras (PROTACs) are an emerging therapeutic modality that show promise to open a target space not accessible to conventional small molecules via a degradation-based mechanism. PROTAC degraders, due to their bifunctional nature, which is categorized as 'beyond the Rule o...

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Main Authors: Rohan Kalyan Rej (Author), Srinivasa Rao Allu (Author), Joyeeta Roy (Author), Ranjan Kumar Acharyya (Author), I. N. Chaithanya Kiran (Author), Yesu Addepalli (Author), V. Dhamodharan (Author)
Format: Book
Published: MDPI AG, 2024-04-01T00:00:00Z.
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3rd Floor Main Library

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