Role of ABCB1 and ABCB4 in renal and biliary excretion of perfluorooctanoic acid in mice

• Asıl Yazarlar: Kazuyoshi Furukawa (Yazar), Kahori Okamoto-Matsuda (Yazar), Kouji H. Harada (Yazar), Mutsuko Minata (Yazar), Toshiaki Hitomi (Yazar), Hatasu Kobayashi (Yazar), Akio Koizumi (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Komiyama Printing Co. Ltd, 2024-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background: Perfluorooctanoic acid (PFOA) is one of the major per- and polyfluoroalkyl substances. The role of ATP-binding cassette (ABC) transporters in PFOA toxicokinetics is unknown. Methods: In this study, two ABC transporters, ABCB1 and ABCB4, were examined in mice with single intravenous PFOA...