3D disorganization and rearrangement of genome provide insights into pathogenesis of NAFLD by integrated Hi-C, Nanopore, and RNA sequencing

• मुख्य लेखकों: Lina Xu (लेखक), Lianhong Yin (लेखक), Yan Qi (लेखक), Xuemei Tan (लेखक), Meng Gao (लेखक), Jinyong Peng (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2021-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The three-dimensional (3D) conformation of chromatin is integral to the precise regulation of gene expression. The 3D genome and genomic variations in non-alcoholic fatty liver disease (NAFLD) are largely unknown, despite their key roles in cellular function and physiological processes. High-through...