Inhibition of oncogene-induced inflammatory chemokines using a farnesyltransferase inhibitor

• প্রধান লেখক: Rothstein Jay L (লেখক), Testa James S (লেখক), DeGeorge Brent R (লেখক), DeGeorge Katharine C (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2008-02-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Farnesyltransferase inhibitors (FTI) are small molecule agents originally formulated to inhibit the oncogenic functions of Ras. Although subsequent analysis of FTI activity revealed wider effects on other pathways, the drug has been...