PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy

• Main Authors: Si-Min Qi (Author), Jinyun Dong (Author), Zhi-Yuan Xu (Author), Xiang-Dong Cheng (Author), Wei-Dong Zhang (Author), Jiang-Jiang Qin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Proteolysis targeting chimeric (PROTAC) technology is an effective endogenous protein degradation tool developed in recent years that can ubiquitinate the target proteins through the ubiquitin-proteasome system (UPS) to achieve an effect on tumor growth. A number of literature studies on PROTAC tech...