PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy

• Главные авторы: Si-Min Qi (Автор), Jinyun Dong (Автор), Zhi-Yuan Xu (Автор), Xiang-Dong Cheng (Автор), Wei-Dong Zhang (Автор), Jiang-Jiang Qin (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Proteolysis targeting chimeric (PROTAC) technology is an effective endogenous protein degradation tool developed in recent years that can ubiquitinate the target proteins through the ubiquitin-proteasome system (UPS) to achieve an effect on tumor growth. A number of literature studies on PROTAC tech...