Quality Control Dissolution Data Is Biopredictive for a Modified Release Ropinirole Formulation: Virtual Experiment with the Use of Re-Developed and Verified PBPK Model

• Hoofdauteurs: Olha Shuklinova (Auteur), Przemysław Dorożyński (Auteur), Piotr Kulinowski (Auteur), Sebastian Polak (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Physiologically based pharmacokinetic and absorption modeling are being used by industry and regulatory bodies to address various scientifically challenging questions. While there is high confidence in the prediction of exposure for the BCS class I drugs administered as immediate-release formulation...