Quality Control Dissolution Data Is Biopredictive for a Modified Release Ropinirole Formulation: Virtual Experiment with the Use of Re-Developed and Verified PBPK Model

• मुख्य लेखकों: Olha Shuklinova (लेखक), Przemysław Dorożyński (लेखक), Piotr Kulinowski (लेखक), Sebastian Polak (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Physiologically based pharmacokinetic and absorption modeling are being used by industry and regulatory bodies to address various scientifically challenging questions. While there is high confidence in the prediction of exposure for the BCS class I drugs administered as immediate-release formulation...