Quality Control Dissolution Data Is Biopredictive for a Modified Release Ropinirole Formulation: Virtual Experiment with the Use of Re-Developed and Verified PBPK Model

• Những tác giả chính: Olha Shuklinova (Tác giả), Przemysław Dorożyński (Tác giả), Piotr Kulinowski (Tác giả), Sebastian Polak (Tác giả)
• Định dạng: Sách
• Được phát hành: MDPI AG, 2022-07-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Physiologically based pharmacokinetic and absorption modeling are being used by industry and regulatory bodies to address various scientifically challenging questions. While there is high confidence in the prediction of exposure for the BCS class I drugs administered as immediate-release formulation...