Folate Receptor Targeted Alpha-Therapy Using Terbium-149

• Autori principali: Cristina Müller (Autore), Josefine Reber (Autore), Stephanie Haller (Autore), Holger Dorrer (Autore), Ulli Köster (Autore), Karl Johnston (Autore), Konstantin Zhernosekov (Autore), Andreas Türler (Autore), Roger Schibli (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2014-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Terbium-149 is among the most interesting therapeutic nuclides for medical applications. It decays by emission of short-range α-particles (Eα = 3.967 MeV) with a half-life of 4.12 h. The goal of this study was to investigate the anticancer efficacy of a 149Tb-labeled DOTA-folate conjugate (cm09) usi...