Advancing peptide siRNA-carrier designs through L/D-amino acid stereochemical modifications to enhance gene silencing

• প্রধান লেখক: Charles E. Holjencin (লেখক), Colton R. Feinberg (লেখক), Travis Hedrick (লেখক), Gregory Halsey (লেখক), Robert D. Williams (লেখক), Priya V. Patel (লেখক), Evan Biles (লেখক), James C. Cummings (লেখক), Chance Wagner (লেখক), Naren Vyavahare (লেখক), Andrew Jakymiw (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2021-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The 599 peptide has been previously shown to effectively deliver small interfering RNAs (siRNAs) to cancer cells, inducing targeted-oncogene silencing, with a consequent inhibition of tumor growth. Although effective, this study was undertaken to advance the 599 peptide siRNA-carrier design through...