Induced Pluripotent Stem Cells Attenuate Acute Lung Injury Induced by Ischemia Reperfusion via Suppressing the High Mobility Group Box-1

• প্রধান লেখক: Yijun Li (লেখক), Shun Wang (লেখক), Jinbo Liu (লেখক), Xingyu Li (লেখক), Meng Lu (লেখক), Xiaokai Wang (লেখক), Yansong Ren (লেখক), Xiaoming Li (লেখক), Meng Xiang (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: SAGE Publishing, 2020-10-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Pulmonary endothelial cell injury is a hallmark of acute lung injury. High-mobility group box 1 (HMGB1) can modulate the inflammatory response via endothelial cell activation and release of inflammatory molecules. Thus, we tested whether induced pluripotent stem cells (iPSCs) can alleviate ischemia/...