Analysis of BCL11A gene polymorphisms and hemolysis parameters in patients with sickle-cell disease

• Hoofdauteurs: Marilia R. Laurentino (Auteur), Maritza C. Barbosa (Auteur), Talyta Ellen J. Santos (Auteur), Anne Caroline B. Perdigão (Auteur), Fernanda M. C. Araújo (Auteur), Romelia P. G. Lemes (Auteur)
• Formaat: Boek
• Gepubliceerd in: Sociedade Brasileira de Patologia Clínica, 2018-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

ABSTRACT Introduction: Patients with sickle-cell disease (SCD) present chronic hemolysis with increased serum biomarkers. Genetic polymorphisms of the BLC11A gene modulate fetal hemoglobin (HbF), thus reducing hemolysis Objective: To associate the polymorphisms of BCL11A gene with the hemolysis mark...