The effects of AP521, a novel anxiolytic drug, in three anxiety models and on serotonergic neural transmission in rats

• Asıl Yazarlar: Ken-ichi Kasahara (Yazar), Shinji Hashimoto (Yazar), Tsuyoshi Hattori (Yazar), Koh Kawasaki (Yazar), Ryuichi Tsujita (Yazar), Osamu Nakazono (Yazar), Katsuyuki Takao (Yazar), Hiromu Kawakubo (Yazar), Tadashi Nagatani (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2015-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

We investigated the anxiolytic effects and mechanism of action of a new anxiolytic drug, (R)-piperonyl-1,2,3,4-tetrahydro[1]benzothieno[2,3-c]pyridine-3- carboxamide hydrochloride (AP521). AP521 showed equal or more potent anxiolytic-like effects compared with diazepam, a benzodiazepine receptor ago...