CYP1B1-derived epoxides modulate the TRPA1 channel in chronic pain

• Main Authors: Lili Sun (Author), Jie Zhang (Author), Changshan Niu (Author), Cassandra E. Deering-Rice (Author), Ronald W. Hughen (Author), John G. Lamb (Author), Katherine Rose (Author), Kevin M. Chase (Author), Marysol Almestica-Roberts (Author), Markel Walter (Author), Eric W. Schmidt (Author), Alan R. Light (Author), Baldomero M. Olivera (Author), Christopher A. Reilly (Author)
• Format: Book
• Published: Elsevier, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pain is often debilitating, and current treatments are neither universally efficacious nor without risks. Transient receptor potential (TRP) ion channels offer alternative targets for pain relief, but little is known about the regulation or identities of endogenous TRP ligands that affect inflammati...