CYP1B1-derived epoxides modulate the TRPA1 channel in chronic pain

• Автори: Lili Sun (Автор), Jie Zhang (Автор), Changshan Niu (Автор), Cassandra E. Deering-Rice (Автор), Ronald W. Hughen (Автор), John G. Lamb (Автор), Katherine Rose (Автор), Kevin M. Chase (Автор), Marysol Almestica-Roberts (Автор), Markel Walter (Автор), Eric W. Schmidt (Автор), Alan R. Light (Автор), Baldomero M. Olivera (Автор), Christopher A. Reilly (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2023-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Pain is often debilitating, and current treatments are neither universally efficacious nor without risks. Transient receptor potential (TRP) ion channels offer alternative targets for pain relief, but little is known about the regulation or identities of endogenous TRP ligands that affect inflammati...