Small-molecule MDM2/X inhibitors and PROTAC degraders for cancer therapy: advances and perspectives

Blocking the MDM2/X-P53 protein-protein interaction has been widely recognized as an attractive therapeutic strategy for the treatment of cancers. Numerous small-molecule MDM2 inhibitors have been reported since the release of the structure of the MDM2-P53 interaction in 1996, SAR405838, NVP-CGM097,...

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Main Authors: Yuan Fang (Author), Guochao Liao (Author), Bin Yu (Author)
Format: Book
Published: Elsevier, 2020-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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