Effect of molecular size on interstitial pharmacokinetics and tissue catabolism of antibodies

• Κύριοι συγγραφείς: Hanine Rafidi (Συγγραφέας), Sharmila Rajan (Συγγραφέας), Konnie Urban (Συγγραφέας), Whitney Shatz-Binder (Συγγραφέας), Keliana Hui (Συγγραφέας), Gregory Z. Ferl (Συγγραφέας), Amrita V. Kamath (Συγγραφέας), C. Andrew Boswell (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Advances in antibody engineering have enabled the construction of novel molecular formats in diverse shapes and sizes, providing new opportunities for biologic therapies and expanding the need to understand how various structural aspects affect their distribution properties. To assess the effect of...