Effect of molecular size on interstitial pharmacokinetics and tissue catabolism of antibodies

• Main Authors: Hanine Rafidi (Author), Sharmila Rajan (Author), Konnie Urban (Author), Whitney Shatz-Binder (Author), Keliana Hui (Author), Gregory Z. Ferl (Author), Amrita V. Kamath (Author), C. Andrew Boswell (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Advances in antibody engineering have enabled the construction of novel molecular formats in diverse shapes and sizes, providing new opportunities for biologic therapies and expanding the need to understand how various structural aspects affect their distribution properties. To assess the effect of...