Propyl Gallate, a Strong Antioxidant, Increases the Ca2+ Sensitivity of Cardiac Myofilament

• Prif Awduron: Naoto Tadano (Awdur), Sachio Morimoto (Awdur), Fumi Takahashi-Yanaga (Awdur), Yoshikazu Miwa (Awdur), Iwao Ohtsuki (Awdur), Toshiyuki Sasaguri (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2009-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Ca2+ sensitizers are cardiotonic agents that directly increase the Ca2+ sensitivity of cardiac myofilament. To find a novel Ca2+ sensitizer, we have screened a group of phenolic compounds by examining their effects on the Ca2+-dependent force generation in cardiac muscle fibers. We found that propyl...