Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway

• Hoofdauteurs: Yuhui Chai (Auteur), Yawen Cai (Auteur), Yu Fu (Auteur), Yingdi Wang (Auteur), Yiming Zhang (Auteur), Xue Zhang (Auteur), Lingpeng Zhu (Auteur), Mingxing Miao (Auteur), Tianhua Yan (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Depression is a common and serious mental disorder. Data on its pathogenesis remain unclear and the options of drug treatments are limited. Here, we explored the role of pyroptosis, a novel pro-inflammatory programmed cell death process, in depression as well as the anti-depression effects and mecha...