Amphiphilic Polypeptides for VEGF siRNA Delivery into Retinal Epithelial Cells

• Asıl Yazarlar: Olga Osipova (Yazar), Vladimir Sharoyko (Yazar), Natalia Zashikhina (Yazar), Natalya Zakharova (Yazar), Tatiana Tennikova (Yazar), Arto Urtti (Yazar), Evgenia Korzhikova-Vlakh (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2020-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Polyethyleneimine, poly-L-lysine, chitosan and some others cationic polymers have been thoroughly studied as nucleic acid delivery systems in gene therapy. However, the drug release from these systems proceeds at a very low rate due to extremely high binding between a carrier and gene material. To r...