Efficacy of the Multi-Target Compound E153 in Relieving Pain and Pruritus of Different Origins

• Hoofdauteurs: Szczepan Mogilski (Auteur), Monika Kubacka (Auteur), Artur Świerczek (Auteur), Elżbieta Wyska (Auteur), Katarzyna Szczepańska (Auteur), Jacek Sapa (Auteur), Katarzyna Kieć-Kononowicz (Auteur), Dorota Łażewska (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Itch and pain are closely related but distinct sensations that share largely overlapping mediators and receptors. We hypothesized that the novel, multi-target compound E153 has the potential to attenuate pain and pruritus of different origins. After the evaluation of sigma receptor affinity and phar...