Efficacy of the Multi-Target Compound E153 in Relieving Pain and Pruritus of Different Origins

• Главные авторы: Szczepan Mogilski (Автор), Monika Kubacka (Автор), Artur Świerczek (Автор), Elżbieta Wyska (Автор), Katarzyna Szczepańska (Автор), Jacek Sapa (Автор), Katarzyna Kieć-Kononowicz (Автор), Dorota Łażewska (Автор)
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• Опубликовано: MDPI AG, 2023-10-01T00:00:00Z.
• Предметы: article
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Itch and pain are closely related but distinct sensations that share largely overlapping mediators and receptors. We hypothesized that the novel, multi-target compound E153 has the potential to attenuate pain and pruritus of different origins. After the evaluation of sigma receptor affinity and phar...