Tubule-specific deletion of LincRNA-p21ameliorates lipotoxic kidney injury

• Príomhchruthaitheoirí: Bin Li (Údar), Joseph C.K. Leung (Údar), Loretta Y.Y. Chan (Údar), Hong-Yu Li (Údar), Wai-Han Yiu (Údar), Sarah W.Y. Lok (Údar), Rui Xue (Údar), Yi-Xin Zou (Údar), Wei Chen (Údar), Kar-Neng Lai (Údar), Sydney C.W. Tang (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2021-12-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Lipotoxicity has been implicated in the pathogenesis of obesity-related kidney damage and propagates chronic kidney injury like diabetic kidney disease; however, the underlying mechanisms have not yet been fully elucidated. To date, reduction of lipid acquisition and enhancement of lipid metabolism...