On the Stability and Degradation Pathways of Venetoclax under Stress Conditions

• मुख्य लेखकों: Nina Žigart (लेखक), Martin Črnugelj (लेखक), Janez Ilaš (लेखक), Zdenko Časar (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Venetoclax is an orally bioavailable, B-cell lymphoma-2 (BCL-2) selective inhibitor, used for the treatment of various types of blood cancers, such as chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). In this study we investigated the degradation of venetoclax under various st...