Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and PDGFR-β related to anticancer drug resistance
With ongoing resistance problems against the marketed EGFR inhibitors having a quinazoline core scaffold there is a need for the development of novel inhibitors having a modified scaffold and, thus, expected lower EGFR resistance problems. An additional problem concerning EGFR inhibitor resistance i...
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Main Authors: | Tim Fischer (Author), Abdulkarim Najjar (Author), Frank Totzke (Author), Christoph Schächtele (Author), Wolfgang Sippl (Author), Christoph Ritter (Author), Andreas Hilgeroth (Author) |
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Format: | Book |
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Taylor & Francis Group,
2018-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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