UPLC-MS/MS for the determination of azilsartan in beagle dog plasma and its application in a pharmacokinetics study

• Váldodahkkit: Cheng Gong (Dahkki), Junfeng Wang (Dahkki), Yinghua Sun (Dahkki), Dawei Ding (Dahkki), Lu Zhong (Dahkki), Meng Zhu (Dahkki), Jin Sun (Dahkki), Xiangrong Zhang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2015-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The purpose of the study is to develop an ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) to determinate the concentration of azilsartan in the dog plasma. After precipitated by methanol, the plasma sample containing azilsartan and diazepam (internal standard, IS) was d...