A Gain-of-Function Mutation in Nav1.6 in a Case of Trigeminal Neuralgia

• Päätekijät: Brian S Tanaka (Tekijä), Peng Zhao (Tekijä), Fadia B Dib-Hajj (Tekijä), Valerie Morisset (Tekijä), Simon Tate (Tekijä), Stephen G Waxman (Tekijä), Sulayman D Dib-Hajj (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2016-08-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Idiopathic trigeminal neuralgia (TN) is a debilitating pain disorder characterized by episodic unilateral facial pain along the territory of branches of the trigeminal nerve. Human pain disorders, but not TN, have been linked to gain-of-function mutations in peripheral voltage-gated sodium...