A Gain-of-Function Mutation in Nav1.6 in a Case of Trigeminal Neuralgia

• Hauptverfasser: Brian S Tanaka (VerfasserIn), Peng Zhao (VerfasserIn), Fadia B Dib-Hajj (VerfasserIn), Valerie Morisset (VerfasserIn), Simon Tate (VerfasserIn), Stephen G Waxman (VerfasserIn), Sulayman D Dib-Hajj (VerfasserIn)
• Format: Buch
• Veröffentlicht: BMC, 2016-08-01T00:00:00Z.
• Schlagworte: article
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Abstract Idiopathic trigeminal neuralgia (TN) is a debilitating pain disorder characterized by episodic unilateral facial pain along the territory of branches of the trigeminal nerve. Human pain disorders, but not TN, have been linked to gain-of-function mutations in peripheral voltage-gated sodium...