S-thanatin functionalized liposome potentially targeting on Klebsiella pneumoniae and its application in sepsis mouse model

• Những tác giả chính: Xiaobo eFan (Tác giả), Juxiang eFan (Tác giả), Xiyong eWang (Tác giả), Pengpeng eWu (Tác giả), Guoqiu eWu (Tác giả)
• Định dạng: Sách
• Được phát hành: Frontiers Media S.A., 2015-10-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

S-thanatin (Ts) was a short antimicrobial peptide with selective antibacterial activity. In this study, we aimed to design a drug carrier with specific bacterial targeting potential. The positively charged Ts was modified onto the liposome surface by linking Ts to the constituent lipids via a PEG li...